发明名称 EXPRESSION LEVELS OF BCL-xL, BCL2, BCL-w, AND BAD AND CANCER THERAPIES
摘要 Described herein are novel methods for treating subjects with a cancer which is not overexpressing at least one of BCL-xL, BCL-w, and BAD, and optionally further overexpressing BCL-2. Also provided herein are tools for determining and/or assessing, and for the administration of, cancer treatments involving BET bromodomain inhibitors, BCL-xL inhibitors, or combinations thereof.
申请公布号 EP3125896(A2) 申请公布日期 2017.02.08
申请号 EP20150717351 申请日期 2015.04.02
申请人 Constellation Pharmaceuticals, Inc. 发明人 CONERY, Andrew, Ryan;MERTZ, Jennifer, Andrea;SIMS, Robert, Joseph, III;CENTORE, Richard, C.
分类号 A61K31/517;A61K31/55;A61K31/551;A61K31/5517;A61P35/00 主分类号 A61K31/517
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