Silicone hydrogels having a structure formed via controlled reaction kinetics

摘要

The present invention relates to a process comprising the steps of reacting a reactive mixture comprising at least one silicone-containing component, at least one hydrophilic component, and at least one diluent to form an ophthalmic device having an advancing contact angle of less than about 80°; and contacting the ophthalmic device with an aqueous extraction solution at an elevated extraction temperature, wherein said at least one diluent has a boiling point at least about 10° higher than said extraction temperature.

主权项

1. A silicone hydrogel formed from a reaction mixture comprising
about 39 to about 75 wt % of at least one slow-reacting hydrophilic monomer;
at least one silicone-containing component; andat least one visible light photoinitiator;wherein at least one of said silicone-containing component, optional additional hydrophilic components or both comprises at least one hydroxyl group and wherein said slow-reacting hydrophilic component and said silicone-containing component are selected to have a conversion ratio at 90% conversion of at least about 20.