Analysis device

摘要

An analysis device for performing analysis about a substance by using an analysis chip having therein a reaction area that reacts with the substance is provided. The analysis device includes: a control section in contact with the analysis chip; a first sensor for measuring an ambient temperature of the analysis chip; a second sensor for measuring the temperature at a contact area of the control section in contact with the analysis chip, and a control circuit for performing feedback control of the control section by finding a temperature of the contact area for achieving a desired temperature of the reaction area based on the ambient temperature measured by the first sensor and a temperature gradient between a position at which the ambient temperature is measured and the reaction area, setting the found temperature as a target value and setting the temperature detected by the second sensor as an output value.

主权项

1. An analysis device configured to perform analysis relating to a substance to be detected, the device comprising:
an analysis chip having therein a reaction area that reacts with the substance to be detected at a predetermined temperature; a temperature control section comprising a heat-transfer member which has a contact area in contact with the analysis chip and is configured to heat or cool the analysis chip to the predetermined temperature via the heat-transfer member; a first temperature sensor configured to measure an ambient temperature at a measurement area of a surface of the analysis chip, wherein the measurement area is different from the contact area; a second temperature sensor configured to measure a contact area temperature at the contact area; and a control circuit comprising an inner memory storing a temperature gradient between the temperature of the measurement area and the temperature of the reaction area; and a drive circuit configured to receive control signals from the control unit to drive the temperature control section, wherein the control circuit is configured to perform feedback control of the temperature control section by receiving a signal representing the contact area temperature and a signal representing the ambient area temperature, calculating a target temperature at the contact area so as to make the reaction area be the predetermined temperature based on the temperature gradient read from the inner memory and the ambient temperature, and sending the control signals according to the calculated target temperature to the drive circuit such that the contact area temperature of the contact area is closer to the target temperature; wherein the analysis chip is disposed such that the bottom surface thereof is in contact with the contact area of the temperature control section so as to have the same temperature as that of the contact area, and wherein the measurement area is included in an opposite surface of the analysis chip from the bottom surface of the analysis chip, wherein the target temperature T2 satisfies the equation below:
T2={1+(b/a)}Tset−(b/a)T1, and wherein a is a distance from the opposite surface to the reaction area, b is a distance from the bottom surface to the reaction area, T1 is the ambient temperature, T2 is the target temperature, and Tset is the predetermined temperature of the reaction area.