| 发明名称 | Nasal drug products and methods of their use | ||
| 摘要 | Drug products adapted for nasal delivery, comprising a pre-primed device filled with a pharmaceutical composition comprising an opioid receptor antagonist, are provided. Methods of treating opioid overdose or its symptoms with the inventive drug products are also provided. | ||
| 申请公布号 | US9561177(B2) | 申请公布日期 | 2017.02.07 |
| 申请号 | US201615183441 | 申请日期 | 2016.06.15 |
| 申请人 | ADAPT PHARMA LIMITED;OPIANT PHARMACEUTICALS | 发明人 | Keegan Fintan;Bell Robert Gerard;Crystal Roger;Weiss Michael Brenner |
| 分类号 | A61M31/00;A61M5/00;A61F13/00;A61K31/56;A61K9/00;A61K9/08;A61K31/485;A61K47/02;A61K47/18;A61M15/08;A61M11/00 | 主分类号 | A61M31/00 |
| 代理机构 | Harness, Dickey & Pierce, P.L.C. | 代理人 | Harness, Dickey & Pierce, P.L.C. |
| 主权项 | 1. A method of treating opioid overdose, the method comprising: delivering a 25-200 μL spray of a pharmaceutical solution from a pre-primed device into a nostril of a patient, wherein the device is adapted for nasal delivery, and wherein the pharmaceutical solution comprises about 4 mg naloxone hydrochloride or a hydrate thereof, between about 0.005% and about 0.015% (w/v) of benzalkonium chloride, and an isotonicity agent. | ||
| 地址 | Dublin IE | ||