Neural interface activity simulator

摘要

Systems and methods to simulate activity that would be recorded using an interface to nerve fibers are provided. Signals, such as motor intent signals, can be converted to neural recordings, such as neural recordings by longitudinal intrafascicular electrodes (LIFEs). Spinal cord motor pools and neural interfaces can be jointly simulated. Realistic simulated neural recordings, such as from electrodes such as LIFEs, can be provided and can be used for the evaluation of decoding algorithms. Systems and methods described herein provide a framework for developing neural interface devices.

主权项

1. A system comprising a non-transitory machine-readable medium having computer-executable instructions for performing a method to simulate activity recorded from an interface to nerve fibers, the method comprising:
simulating generation of at least one signal of a variable capable of being recorded by an interface to nerve fibers; simulating translation of the variable to motor neuron firing; generating a realistic simulated neural recording that corresponds to how a real body would respond to motor neuron stimulus of the nerve fibers; and simulating recording of the motor neuron firing by the interface to nerve fibers, wherein the simulated activity is neural activity, and wherein simulating recording of the motor neuron firing comprises:
generating a virtual electrode;mapping the motor neuron firing to signals of the virtual electrode by a mapping matrix B; andmultiplying a cross-talk matrix C and the mapping matrix B.