| 主权项 |
1. A compound according to formula: or stereoisomers thereof, wherein R1 is selected from the group consisting of methoxy, ethoxy, —SCH3, —SCH2CH3, and —NR8R9; R2 is selected from the group consisting of hydrogen, hydroxyl, alkoxy, amino, aminoalkyl, aminoalkenyl, aminoalkynyl, halide, haloalkyl, hydroxyalkyl, —NHCN, aminocarbonyl, hydroxyaminocarbonyl, alkylaminocarbonyl, acyloxy, nitrile, —CH2CN, lower alkyl, substituted lower alkyl, lower alkenyl, lower alkynyl, —SH, —SCH3, alkoxycarbonyl, alkylcarbonylamino, —NHC(O)—O-lower alkyl, —NHC(O)—O-lower alkenyl, —NHC(O)—O-lower alkynyl, —NHCO-cyclopropyl, —NHCO— haloalkyl, —NHSO2CH3, —NHCSNHCH3, sulfoximine, —CH═NOH, —SOCH3, —SO2CH3, —NHSO2CH3, and —SO2NH2; R3 is selected from the group consisting of hydrogen, halide, haloalkyl, hydroxyl, amino, methylamino, —CH2OH, methoxy, lower alkyl, lower alkenyl, lower alkynyl, acyloxy, alkylcarbonylamino, —C(O)OCH3, nitrile, and —CH2CN; R4 is selected from the group consisting of lower alkyl, substituted lower alkyl, lower alkenyl, substituted lower alkenyl, lower alkynyl, substituted lower alkynyl, alkoxy, alkoxyalkyl, alkoxyalkenyl, alkoxyalkynyl, alkyl ether, alkylthio, alkenylthio, alkynylthio, thioalkyl ether; R8 and R9 are independently selected from the group consisting of hydrogen, lower alkyl, substituted lower alkyl, lower alkenyl, and cycloalkyl, or pharmaceutically acceptable salts, solvates, or prodrugs thereof; provided that R2 is not methoxy when R1 is methoxy, R3 is hydrogen, and R4 is 2-propenyl. |
