发明名称 |
Derivados de ariletinilo |
摘要 |
The present invention relates to ethynyl derivatives of formula I wherein R1 is phenyl, which is optionally substituted by 1-2 halogen atoms; selected from fluorine or chlorine; or to a pharmaceutically acceptable acid addition salt in enantiomerically pure form. It has been found that the compounds of general formula I are allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5). |
申请公布号 |
ES2600133(T3) |
申请公布日期 |
2017.02.07 |
申请号 |
ES20130735315T |
申请日期 |
2013.07.12 |
申请人 |
F. Hoffmann-La Roche AG |
发明人 |
JAESCHKE, Georg;LINDEMANN, Lothar;STADLER, Heinz;VIEIRA, Eric |
分类号 |
C07D209/52;A61K31/403;A61P25/00 |
主分类号 |
C07D209/52 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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