发明名称 Optical coherence imaging systems having a reduced effective linewidth and methods of using the same
摘要 Frequency domain optical coherence imaging systems have an optical source, an optical detector and an optical transmission path between the optical source and the optical detector. The optical transmission path between the optical source and the optical detector reduces an effective linewidth of the imaging system. The optical source may be a broadband source and the optical transmission path may include a periodic optical filter.
申请公布号 US9562856(B2) 申请公布日期 2017.02.07
申请号 US201113168286 申请日期 2011.06.24
申请人 Bioptigen, Inc. 发明人 Izatt Joseph A.;Buckland Eric L.;Brown William J.
分类号 G01B9/02;G01N21/47;A61B3/10;A61B3/12;A61B5/00 主分类号 G01B9/02
代理机构 Myers Bigel, P.A. 代理人 Myers Bigel, P.A.
主权项 1. A frequency domain optical coherence tomography imaging system, the system comprising: an optical splitter; a reference arm and a sample arm coupled to the optical splitter; a source arm coupled to the optical splitter and including an optical source emitting across a total bandwidth that partially defines an axial resolution of the system, wherein the optical splitter receives light from the source arm and directs a first portion of the light from the source arm into the reference arm and a second portion of light from the source arm into the sample arm; an optical coupler that receives light from the reference arm and from the sample arm; a detector arm coupled to the optical coupler, the optical coupler directing a portion of light received from the reference arm and the sample arm to the detector arm; and at least one optical detector in the detector arm, the detector arm receiving light from the optical coupler and directing the light from the optical coupler to the at least one optical detector; wherein a configuration of the sample of the plurality of spectral elements comprises a mapping of a spatial or temporal readout of the at least one optical detector to the wavelength or frequency of a corresponding spectral element; wherein at least one of the source arm, the reference arm, the sample arm and the detector arm comprises a periodic optical filter having an FSR less than a total bandwidth of the source and a finesse greater than two to provide a plurality of spectrally separated spectral elements; wherein the at least one optical detector is configured to sample a plurality of spectral elements at one of substantially equal intervals to the FSR or intervals greater than the FSR of the filter; wherein a spectral spacing is provided between each of the sampled plurality of spectral elements and a bandwidth is associated with each of the sampled plurality of spectral elements; wherein the spectral spacing between each of the sampled plurality of spectral elements partially defines an image depth of the system and the bandwidth associated with each of the sampled plurality of spectral elements partially defines the image depth of the system; and wherein the bandwidth of each of the plurality of spectral elements sampled by the at least one optical detector is less than or equal to one-half the spectral spacing between each of the sampled plurality of spectral elements and less than or equal to one-half the total bandwidth of the optical source.
地址 Morrisville NC US