发明名称 Cosmetic, external skin preparation, and medical instrument
摘要 It is an object of the present invention to provide a cosmetic or external skin preparation that has an improved feel in use, e.g., excellent stretching on the skin surface, excellent permeation into the skin, and no stickiness, or crinkles. A cosmetic or an external skin preparation, and a medical instrument, comprising at least one lipid peptide-based gelator that contains a low-molecular lipid peptide of Formula (1):; (where R1 to R3 are independently an organic group) or a pharmaceutically usable salt thereof.
申请公布号 US9561255(B2) 申请公布日期 2017.02.07
申请号 US201213685202 申请日期 2012.11.26
申请人 NISSAN CHEMICAL INDUSTRIES, LTD.;KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION 发明人 Iwama Takehisa;Matsumoto Keigo;Imoto Takayuki;Miyachi Nobuhide;Goto Masahiro
分类号 A61K38/05;A61K38/39;A61K31/734;A61K31/715;A61K8/64;A61K9/00;A61K9/06;A61K47/10;A61K47/42;A61L15/28;A61L26/00;A61Q19/00;A61K9/12;A61K47/36;A61Q19/02;A61Q19/08;A61K47/48;C07K5/062 主分类号 A61K38/05
代理机构 Oliff PLC 代理人 Oliff PLC
主权项 1. A method for coagulating blood with a medical instrument, the medical instrument comprising: at least one lipid peptide-based gelator that contains a lipid peptide or a pharmaceutically usable salt thereof; and at least one macromolecular compound having blood coagulating activity, wherein: the lipid peptide is represented by Formula (1): where: R1 is a C9-23 aliphatic group;R2 and R3 are independently a hydrogen atom, a methyl group, an ethyl group, a C3-7 alkyl group that optionally contains a C1-3 branched chain, a phenylmethyl group, a phenylethyl group, or a —(CH2)n—X group;at least one of R2 and R3 is a —(CH2)n—X group;n is a number of 1 to 4;X is an amino group, a guanidino group, a carbamoyl group, a 5-membered ring group optionally containing 1 to 3 nitrogen atoms, a 6-membered ring group optionally containing 1 to 3 nitrogen atoms, or a condensed ring group that contains a 5-membered ring and a 6-membered ring optionally containing 1 to 3 nitrogen atoms; andm is 1, wherein the macromolecular compound having blood coagulating activity is gum arabic, and wherein a concentration of the gum arabic is 0.1 to 3% (w/v) relative to the total volume of the medical instrument, the method comprising: contacting the medical instrument with blood, andcoagulating the blood.
地址 Tokyo JP