Análogos de heteroarilamida sustituida como moduladores alostéricos negativos de mGlur5 y métodos de elaboración y utilización de los mismos
摘要
Disclosed are negative allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5); synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating neurological and psychiatric disorders associated with glutamate dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
申请公布号
ES2599989(T3)
申请公布日期
2017.02.06
申请号
ES20100817936T
申请日期
2010.09.17
申请人
Vanderbilt University, Center for Technology Transfer And Commercialization