| 发明名称 |
MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF NUCLEAR PROTEINS |
| 摘要 |
The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules. |
| 申请公布号 |
US2017028085(A1) |
申请公布日期 |
2017.02.02 |
| 申请号 |
US201615294339 |
申请日期 |
2016.10.14 |
| 申请人 |
ModernaTX, Inc. |
发明人 |
BANCEL Stephane;CHAKRABORTY Tirtha;DE FOUGEROLLES Antonin;ELBASHIR Sayda M.;JOHN Matthias;ROY Atanu;WHORISKEY Susan;Wood Kristy M.;HATALA Paul;SCHRUM Jason P.;EJEBE Kenechi;ELLSWORTH Jeff Lynn;GUILD Justin;WEISS Ron |
| 分类号 |
A61K48/00;A61K9/50;C07K14/535;A61K38/19;A61K38/48;C07K14/505;A61K38/18;C07K14/525;C07K14/565;A61K38/21;C07K16/32;A61K39/395;C07K16/28;C07K14/475;A61K38/44;C07K14/56;C07K14/745;A61K38/36;C07K14/75;C12N9/64;C12N9/02;A61K9/127 |
主分类号 |
A61K48/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An mRNA encoding a polypeptide of interest selected from the group consisting of SEQ ID NOs 3858-7559, wherein said mRNA comprises a coding region selected from the group consisting of SEQ ID NOs: 7560-26153. |
| 地址 |
Cambridge MA US |
