| 发明名称 |
COMPOSITIONS AND METHODS FOR INDUCTION OF TH17 CELLS |
| 摘要 |
Strains of human-derived bacteria have been obtained from complex fecal samples and shown to induce accumulation of Th17 cells in the intestine and promote immune functions. Pharmaceutical compositions containing these bacteria can be used as anti-infectives and as adjuvants in mucosal vaccines. |
| 申请公布号 |
US2017028061(A1) |
申请公布日期 |
2017.02.02 |
| 申请号 |
US201515302755 |
申请日期 |
2015.04.10 |
| 申请人 |
RIKEN ;The University of Tokyo ;School Corporation, Azabu Veterinary Medicine Educational Institution |
发明人 |
Honda Kenya;Atarashi Koji;Hattori Masahira;Morita Hidetoshi |
| 分类号 |
A61K39/39;A61K35/745;A61K35/742;A61K35/74;A61K35/741 |
主分类号 |
A61K39/39 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A composition that induces proliferation and/or accumulation of Th17 cells, the composition comprising, as an active component, (a) the ampicillin-resistant bacterial fraction of a fecal sample; or (b) a culture supernatant of one or more bacteria of (a). |
| 地址 |
Wako-shi, Saitama JP |
