COMPOSITIONS AND METHODS FOR TREATING BIOFILMS

摘要

The present invention relates to a novel composition for use in inhibiting or treating microbial biofilm formation, said composition comprising a plant defensin or a peptide derivative thereof and an antifungal compound, preferably caspofungin, anidulafungin, micafungin, or amphotericin B. Accordingly, the present invention relates to use of said composition for the inhibition or treatment of biofilms, particularly fungal biofilms, such as Candida biofilms, in a subject or on a surface or other medium susceptible to biofilm formation.