发明名称 |
HUMAN MONOCLONAL ANTIBODY WITH SPECIFICITY FOR DENGUE VIRUS SEROTYPE 1 E PROTEIN AND USES THEREOF |
摘要 |
Compositions and methods for the treatment or prevention of Dengue virus infection in a vertebrate subject are provided. In particular, human neutralizing monoclonal antibodies to Dengue virus isolated from EBV immortalized B cells derived from patients who have recovered from Dengue infection are disclosed. Methods are provided for administering such antibodies to a vertebrate subject in an amount effective to reduce, eliminate, or prevent relapse from infection. |
申请公布号 |
US2017029489(A1) |
申请公布日期 |
2017.02.02 |
申请号 |
US201615170838 |
申请日期 |
2016.06.01 |
申请人 |
National University Of Singapore ;DSO National Laboratories |
发明人 |
Macary Paul Anthony;Teoh Ee Ping Evelyn;Hanson Brendon John;Teo En Wei;Lim Angeline Pei Chiew;Ng Mah Lee Mary;Lok Shee Mei;Kukkaro Petra Eveliina |
分类号 |
C07K16/10;A61K39/42;A61K45/06 |
主分类号 |
C07K16/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
Singapore SG |