| 发明名称 |
SUBSTITUTED AMIDE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN |
| 摘要 |
The present invention relates to substituted amide derivatives of formula (I) having dual pharmacological activity towards both the sigma (σ) receptor, and the p-opioid receptor, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use in therapy, in particular for the treatment of pain. |
| 申请公布号 |
WO2017016669(A1) |
申请公布日期 |
2017.02.02 |
| 申请号 |
WO2016EP01310 |
申请日期 |
2016.07.28 |
| 申请人 |
LABORATORIOS DEL DR. ESTEVE, S.A. |
发明人 |
GARCIA-LOPEZ, Monica;ALMANSA-ROSALES, Carmen;LLORENTE-FERNANDEZ, Ana, Virginia;GARRIGA-SANAHUJA, Lourdes;CHRISTMANN, Ute |
| 分类号 |
C07D405/14;A61K31/496;A61P25/04;C07D295/12;C07D295/125;C07D295/13;C07D295/135;C07D401/04;C07D401/12;C07D405/04;C07D409/12;C07D409/14;C07D417/14 |
主分类号 |
C07D405/14 |
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