| 发明名称 |
ANTIBODIES AGAINST HUMAN CSF-1R AND USES THEREOF |
| 摘要 |
The present invention relates to antibodies against human CSF-1R (anti-CSF-1R antibody), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof. |
| 申请公布号 |
US2017029517(A1) |
申请公布日期 |
2017.02.02 |
| 申请号 |
US201615292710 |
申请日期 |
2016.10.13 |
| 申请人 |
HOFFMANN-LA ROCHE INC. |
发明人 |
DIMOUDIS Nikolaos;FERTIG Georg;FIDLER Alexander;KALUZA Klaus;THOMAS Marlene;RIES Carola;SEEBER Stefan;LANZENDOERFER Martin |
| 分类号 |
C07K16/28 |
主分类号 |
C07K16/28 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An isolated antibody binding to human CSF-1R, wherein the antibody comprises a heavy chain variable domain and a light chain variable domain, and wherein the heavy chain variable domain comprises a CDR3 region comprising SEQ ID NO: 69, a CDR2 region comprising SEQ ID NO: 70, and a CDR1 region comprising SEQ ID NO: 71, and the light chain variable domain comprises a CDR3 region comprising SEQ ID NO:72, a CDR2 region comprising SEQ ID NO: 73, and a CDR1 region comprising SEQ ID NO: 74. |
| 地址 |
Little Falls NJ US |
