| 发明名称 |
EVOLUTION OF BT TOXINS |
| 摘要 |
The disclosure provides amino acid sequence variants of Bacillus thuringiensis (Bt) toxins and methods of producing the same. Some aspects of this disclosure provide methods for generating Bt toxin variants by continuous directed evolution. Some aspects of this disclosure provide compositions and methods for pest control using the disclosed variant Bt toxins. |
| 申请公布号 |
US2017029473(A1) |
申请公布日期 |
2017.02.02 |
| 申请号 |
US201615217839 |
申请日期 |
2016.07.22 |
| 申请人 |
President and Fellows of Harvard College ;Monsanto Company |
发明人 |
Liu David R.;Badran Ahmed Hussein;Guzov Victor;Malvar Tom;Vishwanath Prashanth;Nageotte Jeff;Huai Qing;Kemp Melissa |
| 分类号 |
C07K14/325;A01N63/02;C12N15/10;C12N15/82 |
主分类号 |
C07K14/325 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A pesticidal protein comprising an amino acid sequence that is at least 95% identical to SEQ ID NO: 1 wherein the protein comprises at least one amino acid sequence variant set forth in Table 1. |
| 地址 |
Cambridge MA US |
