The present invention relates to dual-site BACE1 inhibitors, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease.
申请公布号
WO2017016982(A1)
申请公布日期
2017.02.02
申请号
WO2016EP67447
申请日期
2016.07.21
申请人
F. HOFFMANN-LA ROCHE AG;HOFFMANN-LA ROCHE INC.;ROCHE NIMBLEGEN, INC.
发明人
BEAUCHAMP, Jeremy;FRESKGARD, Per-Ola;KITAS, Eric A.;LYAMICHEV, Victor;PATEL, Jigar
