发明名称 CONCENTRATE CONTAINING ALPROSTADIL
摘要 The invention relates to a liquid pharmaceutical composition in the form of a concentrate for producing an infusion, containing alprostadil (prostaglandin E1) as the active ingredient, dissolved in a solvent mixture consisting of at least one pharmaceutically acceptable organic solvent and water. The invention is characterised in that the total water content in the solvent mixture is from 8 to 85 % by weight H2O, in relation to the total quantity of the solvent mixture, and that at least one acid or a substance acting as an acid or proton donor is contained in the mixture as a stabiliser for the active ingredient.
申请公布号 WO2017015692(A1) 申请公布日期 2017.02.02
申请号 WO2016AT60020 申请日期 2016.07.25
申请人 GEBRO HOLDING GMBH 发明人 HESSE, Ernst;HANSBAUER, Bernhard;HÄUSLER, Franz
分类号 A61K9/00;A61K9/08;A61K31/00;A61K47/10;A61K47/12 主分类号 A61K9/00
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