发明名称 DNA VACCINES AND METHODS FOR THE PREVENTION OF TRANSPLANTATION REJECTION
摘要 Methods for preventing, delaying the onset of, or treating rejection of an allograft using a DNA vaccine, where the vaccine can comprise a polynucleotide encoding a pro-apoptotic protein, like BAX and/or a polynucleotide encoding an autoantigen or donor antigen, like secreted glutamic acid decarboxylase 55. Administering one of the DNA vaccines to a transplant recipient, as described herein, can induce a donor specific tolerogenic response.
申请公布号 US2017028039(A1) 申请公布日期 2017.02.02
申请号 US201615172937 申请日期 2016.06.03
申请人 LOMA LINDA UNIVERSITY 发明人 Li Fengchun;Escher Alan P.
分类号 A61K39/00;A61K45/06;A61K9/00 主分类号 A61K39/00
代理机构 代理人
主权项
地址 Loma Linda CA US