发明名称 |
BILE ACID RECEPTOR AGONISM FOR TREATING ADDICTION |
摘要 |
Compositions and methods for treating addiction in a subject are disclosed. In particular, compositions and methods for treating addiction to a dopaminergic psychostimulant are disclosed. In some embodiments, addiction is treated by agonizing bile acid receptors in the subject. For example, in some embodiments, the method comprises administering to the subject a therapeutically effective amount of a composition comprising a therapeutically effective amount of a bile acid receptor agonist. In some embodiments, the method comprises surgically diverting bile acids in the subject in a manner suitable to increase circulating bile acids in the subject. |
申请公布号 |
WO2017019616(A1) |
申请公布日期 |
2017.02.02 |
申请号 |
WO2016US43891 |
申请日期 |
2016.07.25 |
申请人 |
VANDERBILT UNIVERSITY |
发明人 |
GALLI, Aurelio;REDDY, India A.;ABUMRAD, Naji N.;ERREGER, Kevin;MATTHIES, Heinrich J.;FLYNN, Charles Robb |
分类号 |
A61K31/00;A61K31/575;A61P25/30 |
主分类号 |
A61K31/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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