New polycrystalline form of tenofovir prodrug, and preparation method and application therefor

摘要

The present invention relates to a new crystalline form of 9-[(R)-2-[[(S)-[[[1-(isopropoxycarbonyl)-1-methyl]ethyl]amino]phenoxyphosphinyl]methoxy]propyl]adenine fumarate, and a preparation method and application therefor. Specifically, the present invention relates to a new crystalline form of 9-[(R)-2-[[(S)-[[[1-(isopropoxycarbonyl)-1-methyl]ethyl]amino]phenoxyphosphinyl]methoxy]propyl]adenine fumarate represented by formula (I), characterised in that the XRPD pattern of the crystalline form at least includes 2θ ± 0.20