| 发明名称 |
NEW ENZYMATIC PROCESS FOR THE PREPARATION OF TESTOSTERONE AND ESTERS THEREOF |
| 摘要 |
The present invention relates to a new process for the preparation of testosterone by means of enzymatic hydrolysis of testosterone esters. |
| 申请公布号 |
US2017029863(A1) |
申请公布日期 |
2017.02.02 |
| 申请号 |
US201615206582 |
申请日期 |
2016.07.11 |
| 申请人 |
F.I.S.- FABBRICA ITALIANA SINTETICI S.P.A |
发明人 |
Paio Alfredo;Fogal Stefano;Motterle Riccardo |
| 分类号 |
C12P33/00;C07J9/00 |
主分类号 |
C12P33/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. Process for the preparation of testosterone of formula (I): by enzymatic hydrolysis of a testosterone ester of formula (II): wherein R is a C1-C9 linear or branched alkyl group or is a C3-C9 cyclic or branched cyclic alkyl group, wherein the enzyme is a lipase from Humicola insolens, wherein the DNA sequence encoding the Humicola insolens lipase is genetically modified or not genetically modified, or the enzyme is a lipase from Candida antarctica A. |
| 地址 |
Montecchio Maggiore (VI) IT |
