EFFICIENT TREATMENT OF ATRIAL FIBRILLATION USING THREE-DIMENSIONAL ELECTRICAL POTENTIAL MODEL

摘要

A method for guiding electrophysiology (EP) intervention using a patient-specific electrophysiology model includes acquiring a medical image of a patient subject (S201). Sparse EP signals are acquired over an anatomy using the medical image for guidance (S202). The sparse EP signals are interpolated using a patient specific computational electrophysiology model and a three-dimensional model of EP dynamics is generated therefrom (S203). A rendering of the three-dimensional model is displayed. Candidate intervention sites are received, effects on the EP dynamics resulting from intervention at the candidate intervention sites is simulated using the model, and a rendering of the model showing the simulated effects is displayed (S205).

主权项

1. A method for guiding electrophysiology (EP) intervention using a patient-specific electrophysiology model, comprising:
acquiring a medical image of a region of interest of a patient subject; acquiring a set of sparse EP signals over an anatomy of the region of interest using the acquired medical image for guidance; interpolating the acquired set of sparse EP signals using a patient specific computational electrophysiology model to generate an enlarged set of EP signals, the enlarged set of EP signals including more EP signals than the set of sparse EP signals; generating a three-dimensional model of EP dynamics within the region of interest using the enlarged set of EP signals; displaying a rendering of the generated three-dimensional model to a user; receiving, from the user, a set of one or more candidate intervention sites; simulating effects on the EP dynamics within the region of interest resulting from intervention at the set of one or more candidate intervention sites using the generated three-dimensional model; and displaying a rendering of the three-dimensional model showing the simulated effects to the user.