| 发明名称 |
STABLE FORMULATIONS FOR ANTI-CD19 ANTIBODIES AND ANTIBODY-DRUG CONJUGATES |
| 摘要 |
This disclosure provides optimized formulations for CD19 antibodies and antibody-drug conjugates (ADCs) |
| 申请公布号 |
US2017028062(A1) |
申请公布日期 |
2017.02.02 |
| 申请号 |
US201515301049 |
申请日期 |
2015.04.07 |
| 申请人 |
SEATTLE GENETICS, INC. |
发明人 |
Amsberry Kent;Jiang Shan |
| 分类号 |
A61K39/395;A61K9/08;A61K47/02;A61J1/06;A61K47/34;A61K9/19;A61K47/26;C07K16/28;A61K47/48 |
主分类号 |
A61K39/395 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A stable formulation of an anti-CD19 antibody comprising a phosphate buffer, wherein the anti-CD19 antibody comprises a light chain variable region of SEQ ID NO:1 and a heavy chain variable region of SEQ ID NO:2, wherein the phosphate buffer has a pH value between 5.0 and 7.0. |
| 地址 |
Bothell WA US |
