| 发明名称 |
TREATMENT OF AUTOIMMUNE DISORDERS AND INFECTIONS USING ANTAGONISTS OF SGK1 ACTIVITY |
| 摘要 |
The present invention provides novel methods for treating Th2-mediated immune disorders and enhancing Th1-mediated immune responses in a subject comprising administering to the subject, a pharmaceutical composition comprising a serum-glucocorticoid regulated kinase 1 (SGK1) inhibitor and a pharmaceutically acceptable carrier. Methods for treating a wide range of autoimmune diseases are also taught. The present invention also provides methods for augmenting the treatment of subjects having viral or parasitic infections, or which have cancerous tumors. |
| 申请公布号 |
US2017027915(A1) |
申请公布日期 |
2017.02.02 |
| 申请号 |
US201615062576 |
申请日期 |
2016.03.07 |
| 申请人 |
THE JOHNS HOPKINS UNIVERSITY |
发明人 |
Powell Jonathan David;Heikamp Emily Beth |
| 分类号 |
A61K31/437 |
主分类号 |
A61K31/437 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. (canceled) |
| 地址 |
Baltimore MD US |
