METHODS FOR SUPPRESSING CANCER BY INHIBITION OF TMCC3
摘要
A method for treating cancer includes administering to a subject in need thereof an antibody against a transmembrane and coiled-coil domains protein 3 (TMCC3), wherein the antibody binds to an epitope in an extracellular domain of TMCC3. The antibody binds to an epitope in an intercoil domain of TMCC3. A method of diagnosing or assessing a cancer condition includes assessing a level of expression or activity of a transmembrane and coiled-coil domains protein 3 (TMCC3) in a sample, wherein an increase in the level of expression of activity of TMCC3 as compared to a standard indicates the presence of cancer stem cells in the sample.
申请公布号
EP3123173(A1)
申请公布日期
2017.02.01
申请号
EP20140886988
申请日期
2014.10.28
申请人
Development Center for Biotechnology;DCB-USA LLC;Chang Gung Memorial Hospital;Academia Sinica