| 摘要 |
The present invention is directed to six membered heteroaryl benzamide compounds of formula (I), which are tropomyosin-related kinase (Trk) family protein kinase inhibitors, and hence are useful in the treatment of pain, inflammation, cancer, restenosis, atherosclerosis, psoriasis, thrombosis, a disease, disorder, injury, or malfunction relating to dysmyelination or demyelination or a disease or disorder associated with abnormal activities of nerve growth factor (NGF) receptor TrkA. |
| 申请人 |
Merck Sharp & Dohme Corp.;MSD R & D (China) Co. Ltd. |
发明人 |
MITCHELL, Helen;FRALEY, Mark, E.;COOKE, Andrew, J.;CHEN, Yi-Heng;STUMP, Craig, A.;ZHANG, Xu-Fang;MCCOMAS, Casey, C.;SCHIRRIPA, Kathy;MCWHERTER, Melody;MERCER, Swati, P.;BABAOGLU, Kerim;MENG, Dongfang;WU, Jane;LIU, Ping;WOOD, Harold, B.;BAO, Jianming;LI, Chun Sing;MAO, Qinghua;QI, Zhiqi |
