| 发明名称 |
MUTANT STAPHYLOCOCCAL ANTIGENS |
| 摘要 |
Immunisation with EsxA, EsxB, FhuD 2, Sta011, Hla and a mutant SpA provides striking results in a renal abscess model of S.aureus infection. The mutant SpA has decreased affinity for the Fcy portion of human IgG and for the Fab portion of VH3-containing B cell receptors. |
| 申请公布号 |
EP3122378(A1) |
申请公布日期 |
2017.02.01 |
| 申请号 |
EP20150711523 |
申请日期 |
2015.03.24 |
| 申请人 |
GlaxoSmithKline Biologicals S.A. |
发明人 |
BAGNOLI, Fabio;FIASCHI, Luigi;SCARSELLI, Maria |
| 分类号 |
A61K39/085;A61K39/00;A61K39/39;C07K14/31 |
主分类号 |
A61K39/085 |
| 代理机构 |
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代理人 |
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