| 发明名称 |
C5AR ANTAGONISTS |
| 摘要 |
A process for preparing a compound of formula (ii),
comprising
(a) treating a compound of formula (i) with H 2 and a platinum oxide catalyst under reducing conditions; and
(b) subjecting the product of step (a) to resolution with di-toluoyl-L-tartaric acid to provide compound (ii) in about 97% enantiomeric excess. |
| 申请公布号 |
PL2381778(T3) |
申请公布日期 |
2017.01.31 |
| 申请号 |
PL19880098356T |
申请日期 |
2009.12.21 |
| 申请人 |
|
发明人 |
FAN PINGCHEN;GREENMAN KEVIN LLOYD;LELETI MANMOHAN REDDY;LI YANDONG;POWERS JAY;TANAKA HIROKO;YANG JU;ZENG YIBIN |
| 分类号 |
C07D211/60;A61K31/445;A61K31/451;A61K31/4545;A61K31/5377;A61P37/06;C07D401/06;C07D401/10;C07D401/14;C07D405/10;C07D413/12 |
主分类号 |
C07D211/60 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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