| 摘要 |
The invention relates to a process for the synthesis of the compound of formula (I):wherein R represents a para-methoxybenzyl (PMB) group or the following group:,characterized in that the compound of formula (VII):wherein R is as defined above, is subjected to a reduction reaction, in the presence of LiBH(Et)3, in an organic solvent to yield the compound of formula (I).It is applied in the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid. |
