Array plates for washing samples

摘要

Methods and systems for processing a first solution on a respective primary area of a device with a plurality of primary areas and a plurality of secondary areas are described. A method includes providing the device and dispensing a second solution to a respective secondary area of one or more secondary areas adjacent to the respective primary area, thereby mixing the first solution on the respective secondary area and the second solution on the respective primary area. The method also includes removing at least a portion of the mixed solution.

主权项

1. A method comprising:
providing a device that includes a plurality of primary areas and a plurality of secondary areas, wherein:
one or more secondary areas of the plurality of secondary areas are distinct and separate from a respective primary area and adjacent to the respective primary area;the plurality of primary areas and the plurality of secondary areas are hydrophilic areas surrounded collectively by hydrophobic areas; andthe respective primary area is covered with a first solution; and dispensing a second solution, distinct from the first solution, to a respective secondary area of the one or more secondary areas adjacent to the respective primary area, thereby causing the second solution on the respective secondary area to merge with the first solution on the respective primary area and form a mixed solution that includes the first solution and the second solution, wherein:
the respective primary area is connected to the respective secondary area with a first channel;dispensing the second solution to the respective secondary area includes causing the second solution to flow from the respective secondary area toward the respective primary area via the first channel; andthe second solution has a first velocity at a narrowest portion of the first channel, a product of the first velocity and a width of the first channel at the narrowest portion divided by a kinematic viscosity of the second solution being not more than one.