发明名称 | Anti-CD40 antibodies | ||
摘要 | The present invention provides high affinity anti-CD40 monoclonal antibodies and related compositions, which may be used in any of a variety of therapeutic methods for the treatment of cancer and other diseases. | ||
申请公布号 | US9556278(B2) | 申请公布日期 | 2017.01.31 |
申请号 | US201614995741 | 申请日期 | 2016.01.14 |
申请人 | Apexigen, Inc. | 发明人 | Zhang Yongke;Yu Guo-Liang;Zhu Weimin |
分类号 | A61K39/395;C07K16/28;A61K39/00 | 主分类号 | A61K39/395 |
代理机构 | Cooley LLP | 代理人 | Cooley LLP |
主权项 | 1. An isolated antibody, or an antigen-binding fragment thereof, that binds to CD40, comprising (i) a heavy chain variable region comprising the VHCDR1 region set forth in SEQ ID NO:3, the VHCDR2 region set forth in SEQ ID NO:4, and the VHCDR3 region set forth SEQ ID NO:5; and (ii) a light chain variable region comprising the VLCDR1 region set forth in SEQ ID NO:6, the VLCDR2 region set forth in SEQ ID NO:7, and the VLCDR3 region set forth in SEQ ID NO: 8. | ||
地址 | San Carlos CA US |