| 主权项 |
1. An aqueous soluble polymersome comprising:
(a) one or more hydrophobic fluorescent polymers; and (b) a plurality of amphiphilic diblock copolymers encapsulating the one or more hydrophobic fluorescent polymers, the copolymers each comprising a hydrophobic block that forms a hydrophobic core structure and a hydrophilic block on the surface of the polymersome that is oriented toward an aqueous phase; wherein the hydrophobic block is selected from poly(lactide-co-glycolic acid) (PLGA), polvlactide (PLA), polyglycolide (PGA), polycaprolactone (PCL), poly(methyl methacylate) (PMMA), polydimethylsiloxane (PDMS), polyethylene (PE) and polystyrene (PS); and the hydrophilic block is selected from a hydrophilic polysaccharide, a polyether, polymethacrylate, poly(methacrylic acid), polyacrylic acid, polyacrylate, poly(alkylacrylic acid), poly(alkylacrylate), polyacrylamide, poly(N-isopropylacrylamide), poly(2-ethyl-2-oxazoline), poly(vinyl alcohol), poly(vinyl acid), poly(2-methyloxazoline) and copolymer combinations thereof. |
