发明名称 INHIBITORS OF INFLUENZA VIRUSES REPLICATION
摘要 Methods of inhibiting the replication of influenza viruses in a biological sample or patient, of reducing the amount of influenza viruses in a biological sample or patient, and of treating influenza in a patient, comprises administering to said biological sample or patient an effective amount of a compound represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof, wherein the values of Structural Formula (IA) are as described herein. A compound is represented by Structural Formula (IA) or a pharmaceutically acceptable salt thereof, wherein the values of Structural Formula (IA) are as described herein. A pharmaceutical composition comprises an effective amount of such a compound or pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, adjuvant or vehicle.
申请公布号 SI2442809(T1) 申请公布日期 2017.01.31
申请号 SI20100031307 申请日期 2010.06.17
申请人 Vertex Pharmaceuticals Incorporated 发明人 CHARIFSON Paul;CLARK Michael P.;BANDARAGE Upul K.;BETHIEL Randy S.;COURT John J.;DENG Hongbo;DRUTU Ioana;DUFFY John P.;FARMER Luc;GAO Huai;GU Wenxin;JACOBS Dylan H.;KENNEDY Joseph M.;LEDEBOER Mark W.;LEDFORD Brian;MALTAIS Francois;PEROLA Emanuele;WANG Tiansheng;WANNAMAKER M. Woods;BYRN Randal;ZHOU Yi;LIN Chao;JIANG Min;GERMANN Ursula A.;JONES Steven;SALITURO Francesco G.;KWONG Ann Dak-Yee
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