发明名称 |
uso de anticorpos anti-cgrp e fragmentos de anticorpo para prevenir ou inibir fotofobia ou aversão à luz em sujeitos em necessidade dos mesmos, especialmente os que sofrem de enxaqueca |
摘要 |
The present invention is directed to methods of inhibiting or preventing photophobia in subjects in need thereof using anti-CGRP antibodies or antibody fragments that inhibit photophobia, especially CGRP-associated photophobia. These antibodies and fragments are useful in treating different disorders associated with photophobia such as migraine, cluster headaches and the like. |
申请公布号 |
BR112013029959(A2) |
申请公布日期 |
2017.01.31 |
申请号 |
BR20131129959 |
申请日期 |
2012.05.21 |
申请人 |
ALDERBIO HOLDINGS LLC;THE UNIVERSITY OF IOWA RESEARCH FOUNDATION |
发明人 |
ADISA KUBURAS;ANA RECOBER;ANDREW F. RUSSO;ANN C. RADDANT;BRIAN ROBERT KOVACEVICH;ERIC A. KAISER;JEFFREY T.L. SMITH;JOHN A. LATHAM;LEON F. GARCIA-MARTINEZ |
分类号 |
A61K39/395;A61P27/02;A61P35/00;C07K16/28;G01N33/53 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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