| 发明名称 | Use of vitelline protein B as a microencapsulating additive | ||
| 摘要 | The present invention includes compositions and methods for the use of an encapsulation additive having between about 0.1 to about 30 percent isolated and purified vitelline protein B to provide for mixed and extended release formulations. | ||
| 申请公布号 | US9555073(B2) | 申请公布日期 | 2017.01.31 |
| 申请号 | US201213407427 | 申请日期 | 2012.02.28 |
| 申请人 | THE TEXAS A&M UNIVERSITY SYSTEM;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 发明人 | Ficht Allison R.;Carson Ken;Sheffield Cynthia;Waite John Herbert |
| 分类号 | C07K16/02;C12N15/00;A61K38/17;A61K9/16;A61K9/50;A61K39/00;A61K38/00 | 主分类号 | C07K16/02 |
| 代理机构 | Chalker Flores, LLP | 代理人 | Flores Edwin S.;Chalker Daniel J.;Chalker Flores, LLP |
| 主权项 | 1. A method of making an extended release formulation comprising: providing a recombinant scrambled vitelline protein B (vpB) peptide which retains the same amino acid ratio as the ratio of amino acids 82-187 of the amino acid sequence selected from the group consisting of SEQ ID NO:1 and SEQ ID NO:2; combining the recombinant scrambled peptide, one or more active agents, a crosslinking agent and an alginate; and crosslinking the recombinant scrambled peptide, the one or more active agents, the crosslinking agent and the alginate to form the extended release formulation. | ||
| 地址 | College Station TX US | ||