发明名称 |
NOVEL ANTI-CMET ANTIBODY |
摘要 |
The invention relates to a novel antibody capable of binding specifically to the human c-Met receptor and/or capable of specifically inhibiting the tyrosine kinase activity of said receptor both in a ligand-dependent and in a ligand-independent manner, with an improved antagonistic activity, said antibody comprising a modified hinge region. The invention also relates to a composition comprising such an antibody antagonist to c-Met and its use as a medicament for treating cancer. |
申请公布号 |
HUE029043(T2) |
申请公布日期 |
2017.01.30 |
申请号 |
HUE11722828 |
申请日期 |
2011.06.01 |
申请人 |
Pierre Fabre Medicament |
发明人 |
GOETSCH, Liliane;WURCH, Thierry;BES, Cedric |
分类号 |
A61K39/00;A61P35/00;C07K16/00;C07K16/28;C07K16/30 |
主分类号 |
A61K39/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|