发明名称 Apixaban liquid formulations
摘要 Disclosed is an apixaban liquid formulation in which the stability and solubility of apixaban is improved. Also provided is a method of administering an apixaban liquid formulation. The liquid formulation may comprise apixaban, a vehicle which is water, and at least two solubilizers such as non-ionic surfactant, an ionic surfactant, a hydrophilic polymer, ethanol, a polyhydric alcohol, a polyethylene glycol, and a carbohydrate.
申请公布号 NZ630763(A) 申请公布日期 2017.01.27
申请号 NZ20130630763 申请日期 2013.09.26
申请人 PFIZER INC.;Bristol-Myers Squibb Holdings Ireland 发明人 Lum Susan;Badawy Sherif Ibrahim Farag
分类号 A61K9/08;A61K31/437;A61K47/34;A61K47/36;A61K47/38 主分类号 A61K9/08
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