Amide derivatives of n-urea substituted amino acids as formyl peptide receptor like-1 (fprl-1) receptor modulators

摘要

Disclosed are N-urea amide derivative compounds of formula (II), wherein the substituents as defined in the specification. Also disclosed is the use a compound of formula (II) as a modulator of the N-formyl peptide receptor like-1 (FPRL-1) receptor for treating ocular inflammatory diseases. An example of a compound of formula (II) is: (2S,3S)-N-(2-amino-2-oxoethyl)-2-{ [(4-bromophenyl) carbamoyl]amino} -3-methylpentanamide