发明名称 Neprilysin inhibitors
摘要 In one aspect, the invention relates to compounds having the formula XII: where Ra, Rb, R2, R7, and X are as defined in the specification, or a pharmaceutically acceptable salt thereof. The compounds described herein are prodrugs of compounds having neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising these compounds; methods of using these compounds; and processes and intermediates for preparing these compounds.
申请公布号 NZ702749(A) 申请公布日期 2017.01.27
申请号 NZ20130702749 申请日期 2013.06.06
申请人 THERAVANCE BIOPHARMA R&D IP LLC 发明人 Fleury Melissa;Hughes Adam
分类号 C07D231/18;A61K31/415;A61K31/4192;A61K31/42;A61K31/4439;A61P9/12;A61P13/12;C07D249/04;C07D249/12;C07D253/08;C07D257/04;C07D261/18;C07D401/04;C07D405/12 主分类号 C07D231/18
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