USE OF ONCOLYTIC HERPES SIMPLEX VIRUS, ALONE OR IN COMBINATION WITH IMMUNE CHECKPOINT INHIBITOR, IN THE TREATMENT OF CANCER

摘要

An oncolytic herpes simplex virus is disclosed for use in a method of treating cancer, the method comprising administering one or more doses of an oncolytic herpes simplex virus effective to induce a Th1 immune response in the subject, and optionally administering a therapeutically effective amount of an immune checkpoint inhibitor.