| 发明名称 |
VACCINE COMPOSITIONS |
| 摘要 |
The present invention relates to the use of an excipient which is a compound of formula (I) or a physiologically acceptable salt or ester thereof: wherein: R1 represents C1-6alkyl; R2 represents hydrogen or C1-6alkyl; and R3 represents C1-6alkyl, for increasing the immunogenicity of an influenza antigen, which use comprises (a) freezing, (b) heat-treating, and/or (c) freeze-drying an aqueous composition comprising the influenza antigen and the excipient.; |
| 申请公布号 |
US2017021008(A1) |
申请公布日期 |
2017.01.26 |
| 申请号 |
US201515302630 |
申请日期 |
2015.04.08 |
| 申请人 |
Stabilitech Ltd. |
发明人 |
DREW Jeffrey |
| 分类号 |
A61K39/145;C12N7/00;A61K9/19;A61K39/39 |
主分类号 |
A61K39/145 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for increasing the immunogenicity of an influenza antigen, said method comprising (a) freezing, (b) heat-treating, and/or (c) freeze-drying an aqueous composition comprising the influenza antigen and an excipient which is a compound of formula (I) or a physiologically acceptable salt or ester thereof:wherein:
R1 represents hydrogen or C1-6 alkyl; R2 represents C1-6 alkyl; and R3 represents C1-6 alkyl. |
| 地址 |
Sussex GB |
