| 发明名称 |
SODIUM CHANNEL BLOCKERS FOR SKIN DISORDERS |
| 摘要 |
Provided are methods of treating a variety of disorders of the skin with inhibitors of the epithelial sodium channel (ENaC). The inhibitors are represented by formula (I)-(IV):;;where R is defined herein. |
| 申请公布号 |
US2017020870(A1) |
申请公布日期 |
2017.01.26 |
| 申请号 |
US201615047274 |
申请日期 |
2016.02.18 |
| 申请人 |
Johnson Michael Ross;Thelin William Robert;Boucher Richard C. |
发明人 |
Johnson Michael Ross;Thelin William Robert;Boucher Richard C. |
| 分类号 |
A61K31/4965;A61K9/00 |
主分类号 |
A61K31/4965 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of treating a disorder of the skin in a human in need thereof comprising administering to the human an effective amount of a compound represented by formula (I)-(IV): Wherein or a pharmaceutically acceptable salt thereof. |
| 地址 |
Chapel Hill NC US |
