MIC REDUCTION WITH LITHIUM IONS

摘要

The invention relates to a process for reducing the minimum inhibitory concentration (MIC) of a biocide against at least one strain of bacteria and/or at least one strain of yeast and/or at least one strain of mould in an aqueous preparation. The invention further relates to the use of a water soluble source of lithium ions for reducing the minimum inhibitory concentration (MIC) of a biocide against at least one strain of bacteria and/or at least one strain of yeast and/or at least one strain of mould in an aqueous preparation.

主权项

1. Process for reducing the minimum inhibitory concentration (MIC) of a biocide against at least one strain of bacteria and/or at least one strain of yeast and/or at least one strain of mould in an aqueous preparation, the process comprising the steps of:
a) providing an aqueous preparation, b) providing at least one biocide, c) providing at least one water soluble source of lithium ions, d) contacting the aqueous preparation of step a) with the at least one biocide of step b), wherein the at least one biocide is effective against at least one strain of bacteria and/or at least one strain of yeast and/or at least one strain of mould when present in the aqueous preparation, e) contacting the aqueous preparation of step a) before and/or during and/or after step d) with the at least one water soluble source of lithium ions of step c) in an amount such that the minimum inhibitory concentration (MIC) of the at least one biocide against the at least one strain of bacteria and/or at least one strain of yeast and/or at least one strain of mould fulfils the equation (I)
MICwithoutLi/MICLi≧1.1  (I) wherein MICwithoutLi is the minimum inhibitory concentration (MIC) of the at least one biocide against the at least one strain of bacteria and/or at least one strain of yeast and/or at least one strain of mould without the at least one water soluble source of lithium ions in ppm, calculated relative to the weight of water in the aqueous preparation of step a), MICLi is the minimum inhibitory concentration (MIC) of the at least one biocide against the at least one strain of bacteria and/or at least one strain of yeast and/or at least one strain of mould with the at least one water soluble source of lithium ions in ppm, calculated relative to the weight of water in the aqueous preparation of step a), wherein the at least one water soluble source of lithium ions is present in the water phase of the aqueous preparation such that the total amount of lithium ions is from 15.0 to 800.0 mMol/L, calculated relative to the weight of water in the aqueous preparation, and wherein the at least one biocide is present in the water phase of the aqueous preparation in an amount of from 0.4 to 6 500.0 ppm, calculated relative to the weight of water in the aqueous preparation.