发明名称 |
COMPOSITIONS AND METHODS FOR SCREENING T CELLS WITH ANTIGENS FOR SPECIFIC POPULATIONS |
摘要 |
Compositions and methods for isolating patient -derived antigen-specific T cells include an antigen complex having a polynucleotide barcoded nanoparticle sorting agent complexed with a peptide-loaded streptavidin major histocompatability complex (MHC) tetramer, the barcoding technology allowing for high fidelity screening of a library of the antigen complexes to readily isolate and identify antigen-specific T cells. |
申请公布号 |
WO2016196691(A3) |
申请公布日期 |
2017.01.26 |
申请号 |
WO2016US35357 |
申请日期 |
2016.06.01 |
申请人 |
CALIFORNIA INSTITUTE OF TECHNOLOGY |
发明人 |
HEATH, James R.;PENG, Songming |
分类号 |
C12Q1/68;G01N33/52;G01N33/53;G01N33/543 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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