发明名称 RADIOLABELLED ANTIBODY FRAGMENTS FOR USE IN TREATING CANCER
摘要 Provided herein are methods, kits, and compositions for stratifying and treating subjects, e.g., subjects having cancer. In some examples, the methods involve use of a radiolabelled heavy chain variable domain derived from a heavy chain antibody (VHH), or a functional fragment thereof, as both a screening agent and a treatment agent. In some examples, the VHH, or a functional fragment thereof, that is radiolabelled with a radioisotope that is both a γ-emitter and β-emitter.
申请公布号 WO2017013026(A1) 申请公布日期 2017.01.26
申请号 WO2016EP66934 申请日期 2016.07.15
申请人 VRIJE UNIVERSITEIT BRUSSEL 发明人 LAHOUTTE, Tony;D'HUYVETTER, Matthias;DE VOS, Jens;DEVOOGDT, Nick
分类号 A61K51/10;A61K101/02;A61K103/30;A61P35/00;C07K16/32 主分类号 A61K51/10
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