| 发明名称 |
MONOCLONAL ANTIBODY AND VACCINE TARGETING FILAMENTOUS BACTERIOPHAGE |
| 摘要 |
Described here is a method for reducing or preventing Pseudomonas aeruginosa biofilm formation in a human subject in need thereof, comprising administering to the human subject a first composition comprising (a) an antigen-binding polypeptide that binds Pf-family bacteriophage, or (b) a vaccine against Pf-family bacteriophage. Also described is an antigen-binding polypeptide that binds specifically to a CoaB protein of Pf-family bacteriophage or fragment thereof. |
| 申请公布号 |
US2017021020(A1) |
申请公布日期 |
2017.01.26 |
| 申请号 |
US201615219073 |
申请日期 |
2016.07.25 |
| 申请人 |
The Board of Trustees of the Leland Stanford Junior University ;University of Washington |
发明人 |
Bollyky Paul L.;Parks William;Secor Patrick |
| 分类号 |
A61K39/395;A61K45/06;C07K16/08;A61K39/12;C12N7/00 |
主分类号 |
A61K39/395 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for reducing or preventing Pseudomonas aeruginosa biofilm formation in a human subject in need thereof, comprising administering to the human subject a first composition comprising (a) an antigen-binding polypeptide that binds Pf-family bacteriophage, or (b) a vaccine against Pf-family bacteriophage. |
| 地址 |
Stanford CA US |
