发明名称 SOLID PHARMACEUTICAL COMPOSITIONS FOR TREATING HCV
摘要 The present invention features solid pharmaceutical compositions comprising Compound 1 and Compound 2. In one embodiment, the solid pharmaceutical composition includes (1) a first layer which comprises 100 mg Compound 1, as well as a pharmaceutically acceptable hydrophilic polymer and a pharmaceutically acceptable surfactant, all of which are formulated in amorphous solid dispersion; and (2) a second layer which comprises 40 mg Compound 2, as well as a pharmaceutically acceptable hydrophilic polymer and a pharmaceutically acceptable surfactant, all of which are formulated in amorphous solid dispersion.
申请公布号 WO2017015211(A1) 申请公布日期 2017.01.26
申请号 WO2016US42806 申请日期 2016.07.18
申请人 ABBVIE INC. 发明人 ASMUS, Katharin;GAO, Yi;GARRETT, Colleen;HACH, Harald;JAYASANKAR, Adivaraha;KYEREMATENG, Samuel;LANDER, Ute;MUELLER, Thomas;NARIS, Marius;OBERMILLER, Constanze;REUL, Regina;SCHNEIDER, Katrin;SEVER, Nancy;SIIMON, Michael;STEITZ, Benedikt;TONG, Ping;WESTEDT, Ulrich;ZHU, Donghua
分类号 A61K9/14;A61K9/20;A61K9/24;A61K31/454;A61K31/498;A61P31/14 主分类号 A61K9/14
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