发明名称 Biomarkers and Therapeutic Targets for Abnormal Retinal Pigment Epithelium
摘要 The present invention relates to markers and therapeutic targets of abnormal retinal pigment epithelium (RPE).
申请公布号 US2017022562(A1) 申请公布日期 2017.01.26
申请号 US201515113444 申请日期 2015.01.23
申请人 GEORGETOWN UNIVERSITY 发明人 GOLESTANEH Nady
分类号 C12Q1/68 主分类号 C12Q1/68
代理机构 代理人
主权项 1. A method of determining if the retinal pigment epithelium (RPE) of a subject having RPE is abnormal, the method comprising a) measuring levels of microRNA-184 (miR-184) in RPE obtained from the subject, and b) comparing the measured levels of miR-184 in the RPE obtained from the subject with normal levels of miR-184, to determine if the subject's levels of miR-184 in RPE are reduced compared to the normal levels of miR-184, wherein a decrease in the levels of miR-184 compared to normal levels of miR-184 is indicative that the subject's RPE is abnormal.
地址 Washington DC US