主权项 |
1. A method of determining if the retinal pigment epithelium (RPE) of a subject having RPE is abnormal, the method comprising
a) measuring levels of microRNA-184 (miR-184) in RPE obtained from the subject, and b) comparing the measured levels of miR-184 in the RPE obtained from the subject with normal levels of miR-184, to determine if the subject's levels of miR-184 in RPE are reduced compared to the normal levels of miR-184, wherein a decrease in the levels of miR-184 compared to normal levels of miR-184 is indicative that the subject's RPE is abnormal. |